Dalla medicina reattiva alla medicina di precisione


  • Sandra La Rosa U.O. Nefrologia e Dialisi, P.O. “Giovanni Paolo II”, Sciacca (AG) - Italy https://orcid.org/0000-0003-2685-9502
  • Chiara Guglielmo U.O. Nefrologia e Dialisi, P.O. “Giovanni Paolo II”, Sciacca (AG) - Italy
  • Alessandra Ocello U.O. Nefrologia e Dialisi, P.O. “Giovanni Paolo II”, Sciacca (AG) - Italy https://orcid.org/0000-0002-8649-3269
  • Concetto Sessa U.O.C Nefrologia e Dialisi, P.O. “Maggiore”, Modica (RG) - Italy
  • Giuseppe Seminara U.O.C. Nefrologia e Dialisi Azienda Ospedaliera Cannizzaro, Catania (CT) - Italy
  • Antonio Granata U.O.C. Nefrologia e Dialisi Azienda Ospedaliera Cannizzaro, Catania (CT) - Italy



Parole chiave:

Genomics, Patient characterization, Personalized medicine, Precision medicine, Transcriptomics


In recent years, there has been increased awareness of a concept of medicine based on individual differences taking into consideration genetic variability, environment, characteristics of the microbiome and individual lifestyles. It makes use of genomics, transcriptomics, proteomics and metabolomics techniques, obtaining a large amount of information which enables a more precise characterization of the patient. This model expands to the principles of prediction, prevention, personalization and participation, including all medical specialties. In nephrology, the application of precision medicine could play a central role, thanks to the information available today in multiple fields: for example the impact of alterations in the intestinal microbiota on the progression of chronic renal failure, in polycystic disease, in diabetic nephropathy and in the personalized approach to the transition period before the beginning of hemodialysis therapy.

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Come citare

La Rosa S, Guglielmo C, Ocello A, Sessa C, Seminara G, Granata A. Dalla medicina reattiva alla medicina di precisione. G Clin Nefrol Dial [Internet]. 18 settembre 2021 [citato 15 ottobre 2021];33:112-9. Available at: https://journals.aboutscience.eu/index.php/gcnd/article/view/2316



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