Any news in Kidney Transplantation?

Abstract

A kidney transplant allows better quality of life for patients with end-stage renal disease, even if the number of available organs still falls short of the actual need. Living-donor and HLA-incompatible kidney transplants have been reported to be good options. A systematic literature review has shown that preemptive living donor kidney transplant (when the patient is not yet on dialysis) is associated with better patient and graft survival in addition to lower rates of acute rejection and delayed graft function. A multicenter observational study found that HLA-incompatible kidney transplant – although burdened by a high risk of infection and immune complications – can offer patients a survival benefit compared to receiving a kidney from a deceased donor or remaining on the waiting list. In conclusion, preemptive living donor and HLA-incompatible kidney transplants are good therapeutic options in our everyday clinical practice, associated not only with better quality of life but also better survival rates.