Nutritional therapy in chronic kidney disease

Authors

  • Antonio Santoro Comitato tecnico scientifico ANED - Milano (Italy) https://orcid.org/0000-0001-9925-8957
  • Dino Gibertoni UOC Ricerca e Innovazione, IRCCS Azienda Ospedaliero-Universitaria di Bologna
  • Andrea Ambrosini UOC Nefrologia e Dialisi ASST Sette Laghi,Varese
  • Ciro Esposito UOC Nefrologia- Fondazione IRCCS S.Maugeri, Pavia
  • Gianvincenzo Melfa UOC Nefrologia ASST Lariana, Lecco - Italy
  • Federico Alberici UOC Nefrologia Presidio Spedali Civili Brescia, Brescia (Italy)
  • Giuseppe Vanacore Presidente, Aned - Milano (Italy)

DOI:

https://doi.org/10.33393/gcnd.2024.3036

Keywords:

Chronic kidney disease, Low-protein diet, Pre-dialysis clinics, Protein-free foods, Renal insufficiency

Abstract

Dietary-Nutritional Therapy (DNT) is an essential component of the conservative management of patients with chronic kidney disease (CKD) as it helps to maintain the optimal nutritional status and to prevent and/or correct symptoms and complications of CKD. Moreover, it allows adherent patients to delay the onset of dialysis, leading to an improved quality of life and cost savings for both patients and the community. Through a survey, we aimed to evaluate how personalized diets were assessed, administered, and experienced by CKD patients. A questionnaire was administered to 180 patients from 4 Nephrology Centers in Lombardy (Italy) regarding their CKD and nutritional therapy. It showed that 73% of patients received dietary prescriptions. In 40% of cases, dietary prescriptions were administered in dedicated clinics and were valued as much as pharmacological ones. Most diets prescribed were low-protein diets (0.8 g protein per kg of body weight), although some included very low protein diets supplemented with keto analogues. Unfortunately, after the initial prescription, the monitoring of the adherence to nutritional therapy is not particularly frequent. In conclusion, our survey suggests that while patients in different Nephrology Centers receive proper dietary prescriptions and follow-ups, there is space for improvement with positive implications for CKD progression, delaying dialysis therapy.

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References

Santoro A. La Malattia Renale Cronica in Italia, i numeri e i costi | Sanità24 Il . Sole 24 Ore. 11.03.2016. https://www.sanita24.ilsole24ore.com/art/medicina-e-ricerca/2016-03-11/la-malattia-renale-cronica-italia-numeri-e-costi-104146.php?uuid=ACLp3JmC&refresh_ce=1 (Accessed February 2024)

Tarun T, Ghanta SN, Ong V, et al. Updates on New Therapies for Patients with CKD. Kidney Int Rep. 2023;9(1):16-28. https://doi.org/10.1016/j.ekir.2023.10.006 PMID:38312786 DOI: https://doi.org/10.1016/j.ekir.2023.10.006

Giordano C. L’utilizzazione dell’urea e dell’ammonio per il mantenimento del bilancio azotato nell’uomo. Boll Soc Ital Biol Sper. 1961;38:1198-1199. PMID:13898812

Goraya N, Wesson DE. Dietary approaches to kidney diseases. In: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner and Rector’s The Kidney. 11th ed. Elsevier; 2020:chap 60.

Rhee CM, Ahmadi SF, Kovesdy CP, Kalantar-Zadeh K. Low-protein diet for conservative management of chronic kidney disease: a systematic review and meta-analysis of controlled trials. J Cachexia Sarcopenia Muscle. 2018;9(2):235-245. https://doi.org/10.1002/jcsm.12264 PMID:29094800 DOI: https://doi.org/10.1002/jcsm.12264

Chang G, Shih HM, Pan CF, Wu CJ, Lin CJ. Effect of Low Protein Diet Supplemented with Ketoanalogs on Endothelial Function and Protein-Bound Uremic Toxins in Patients with Chronic Kidney Disease. Biomedicines. 2023;11(5):1312. https://doi.org/10.3390/biomedicines11051312 PMID:37238983 DOI: https://doi.org/10.3390/biomedicines11051312

Yan B, Su X, Xu B, Qiao X, Wang L. Effect of diet protein restriction on progression of chronic kidney disease: A systematic review and meta-analysis. PLoS One. 2018;13(11):e0206134. https://doi.org/10.1371/journal.pone.0206134 PMID:30403710 DOI: https://doi.org/10.1371/journal.pone.0206134

Pieroni A, Pezzana A, Borgio C, Pasticci F, Vanacore G. Una alimentazione che ti sia amica-nutrizione e Nefropatia”. Milano 2019. Aned Onlus.

Published

2024-03-04

How to Cite

Santoro, A., Gibertoni, D., Ambrosini, A., Esposito, C., Melfa, G., Alberici, F., & Vanacore, G. (2024). Nutritional therapy in chronic kidney disease. Giornale Di Clinica Nefrologica E Dialisi, 36(1), 7–9. https://doi.org/10.33393/gcnd.2024.3036
Received 2024-02-05
Accepted 2024-02-15
Published 2024-03-04

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