The impact of antimicrobial stewardship programs on the appropriateness of prophylaxis and antimicrobial therapy: the experience of the “F. Miulli” Hospital of Bari

Authors

  • Vincenzo Picerno UOC Farmacia Ospedaliera, Ente Ecclesiastico Ospedale Generale Regionale “F. Miulli”, Acquaviva delle Fonti, Bari - Italy
  • Gisella Caracciolo UOC Anestesia e Rianimazione, Ente Ecclesiastico Ospedale Generale Regionale “F. Miulli”, Acquaviva delle Fonti, Bari - Italy
  • Martina Cortelletti UOC Farmacia Ospedaliera, Ente Ecclesiastico Ospedale Generale Regionale “F. Miulli”, Acquaviva delle Fonti, Bari - Italy
  • Maurizio Formoso Direzione Sanitaria, Ente Ecclesiastico Ospedale Generale Regionale “F. Miulli”, Acquaviva delle Fonti, Bari - Italy
  • Vincenzo Longobardo UOC Medicina Interna, Ente Ecclesiastico Ospedale Generale Regionale “F. Miulli”, Acquaviva delle Fonti, Bari - Italy
  • Angela Moramarco UOC Patologia Clinica, Ente Ecclesiastico Ospedale Generale Regionale “F. Miulli”, Acquaviva delle Fonti, Bari - Italy
  • Fabrizio Celani Direttore Sanitario, Ente Ecclesiastico Ospedale Generale Regionale “F. Miulli”, Acquaviva delle Fonti, Bari - Italy

DOI:

https://doi.org/10.33393/ao.2021.2199

Keywords:

Antimicrobial stewardship, Antimicrobial stewardship programs, Multidisciplinary group, Surgical wards

Abstract

Introduction: The continuous increase of antimicrobial resistance (AMR) requires antimicrobial stewardship programs (ASPs) to optimize antimicrobial use, including selection, dose, duration, and way of administration.

Methods and Results: An “Antimicrobial Stewardship Team” (AST) was established at “F. Miulli” Hospital of Bari. The AST is a multidisciplinary group formed by a pharmacist, an infectious disease specialist, a microbiologist, an anesthetist and a hygienist. The AST has started a clinical path of professional interactions and optimization of antimicrobial use. The AST was focused on surgical antibiotic prophylaxis, planning events/meetings with 13 wards of “F. Miulli” hospital and writing 13 operating guidelines. The AST was focused on antimicrobial therapies too. On this occasion, the AST did not organize events or meetings but was focused on professional interactions with clinicians to optimize the antimicrobial use in the treatment of multi-drug resistant (MDR) pathogens. A reduction of antimicrobial use (defined daily dose, DDD) and pharmaceutical expenditure was reached in surgical wards during 2017-2018, while, in the same period, an increase of antimicrobial use (DDD) and pharmaceutical expenditure was observed in non-surgical wards.

Conclusions: The “Antimicrobial Stewardship Team” programs are essential to monitor the hospital economic resources and to support the purchase of the innovative antimicrobial therapies to treat multi-drug resistant pathogens.

References

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Published

2021-02-11

How to Cite

1.
Picerno V, Caracciolo G, Cortelletti M, Formoso M, Longobardo V, Moramarco A, Celani F. The impact of antimicrobial stewardship programs on the appropriateness of prophylaxis and antimicrobial therapy: the experience of the “F. Miulli” Hospital of Bari. abtpn [Internet]. 2021 Feb. 11 [cited 2021 Oct. 24];8(1):6-13. Available from: https://journals.aboutscience.eu/index.php/aboutopen/article/view/2199

Issue

Section

Original research article