Clinical research

9 Items

This section covers design, conduct, analysis, and interpretation of clinical studies involving patients, focusing on efficacy, safety, outcomes, and real‑world evidence to inform best practices, guidelines, and evidence‑based decision‑making across medical disciplines.

Section Editor: Celeste Cagnazzo
Ospedale infantile Regina Margherita, Senior Clinical Research Coordinator & Project Manager | Turin, Italy

All Items

From data to evidence: the evolving role of observational studies and target trial emulation in regulatory decision-making

Maurizio Polignano, Ruggero Lasala, Romina Giannini, Andrealuna Ucciero, Alessia Romagnoli, Valentina Isgrò, Fiorenzo Santoleri, Alberto Costantini

43-46

DOI: https://doi.org/10.33393/ao.2025.3645
Good clinical practice revision 3: evolution or revolution?

Celeste Cagnazzo, Francesca Resente, Linda Penolazzi, Franca Fagioli

27-32

DOI: https://doi.org/10.33393/ao.2025.3595
Pharmacovigilance in no profit clinical research. Requirements and challenges

Celeste Cagnazzo, Veronica Franchina

66-68

DOI: https://doi.org/10.33393/ao.2024.3097
How to manage symptoms in pediatric cancer patients enrolled in clinical trials? A review of principal patient-reported outcome screening tools

Giulia Zucchetti , Celeste Cagnazzo, Sabrina Ciappina, Nicoletta Bertorello, Francesca Resente , Manuela Spadea , Valeria Ceolin, Franca Fagioli

110-118

DOI: https://doi.org/10.33393/ao.2023.2630
Clinical research: the great absentee of the Italian University training programs?

Stefano Stabile, Veronica Franchina, Rosita Cenna, Valentina Sinno, Francesca Mannozzi, Irene Federici, Sara Testoni, Celeste Cagnazzo

64-68

DOI: https://doi.org/10.33393/ao.2023.2566
Patient Reported Outcomes from research to clinical practice. Opportunities and future challenges

Elisabetta Iannelli

60-63

DOI: https://doi.org/10.33393/ao.2023.2575
Management of patients with chronic rhinosinusitis and nasal polyposis in Italy: expert opinion on the diagnostic-therapeutic approach

Francesco Menzella, Diego Bagnasco, Maria Beatrice Bilò, Marco Caminati, Carlo Cavaliere, Marco Contoli, Alessio De Massimi, Stefania Gallo, Andrea Matucci, Giancarlo Ottaviano, Oliviero Rossi, Veronica Seccia, Martino Emmi, Frank Rikki Canevari

43-49

DOI: https://doi.org/10.33393/ao.2023.2555
Decentralized Clinical Trials in Italy: state of the art and future perspectives

Elisa Zagarrì, Stefania Frasson, Antonella Valerio, Gualberto Gussoni

22-26

DOI: https://doi.org/10.33393/ao.2023.2546
Clinical trial units and clinical research coordinators: a system facing crisis?

Stefano Stabile, Rosita Cenna, Valentina Sinna, Franchina Veronica, Francesca Mannozzi, Irene Federici, Sara Testoni, Celeste Cagnazzo

1-3

DOI: https://doi.org/10.33393/ao.2023.2508