Approccio nutrizionale all’ipofosforemia post-trapianto di rene: uno studio pilota

Autori

  • Alessandra Zattarin UOC Dietetica e Nutrizione Clinica, Dipartimento di Medicina (DIMED), Università di Padova - Italy
  • Francesco Francini-Pesenti UOC Dietetica e Nutrizione Clinica, Dipartimento di Medicina (DIMED), Università di Padova - Italy https://orcid.org/0000-0003-4370-3411
  • Claudia Da Col UOC Dietetica e Nutrizione Clinica, Dipartimento di Medicina (DIMED), Università di Padova - Italy https://orcid.org/0000-0002-8945-824X
  • Paolo Spinella UOC Dietetica e Nutrizione Clinica, Dipartimento di Medicina (DIMED), Università di Padova - Italy https://orcid.org/0000-0002-5979-9203
  • Marianna Alessi UOC Nefrologia, Dipartimento di Medicina (DIMED), Università di Padova - Italy
  • Lucia Federica Stefanelli UOC Nefrologia, Dipartimento di Medicina (DIMED), Università di Padova - Italy
  • Lorenzo A. Calò UOC Nefrologia, Dipartimento di Medicina (DIMED), Università di Padova - Italy https://orcid.org/0000-0002-7534-0128

DOI:

https://doi.org/10.33393/gcnd.2022.2472

Parole chiave:

Diet, Hypophosphatemia, Kidney transplant

Abstract

Renal transplantation is the gold standard for the treatment of ESRD patients. During the early-stage post-transplantation, metabolic and electrolytic alterations may develop, including hypophosphatemia and the treatment includes a diet rich in phosphorus, sometimes with the addition of oral or intravenous phosphorus supplement. Forty-four kidney transplanted patients with hypophosphatemia were evaluated retrospectively. They were divided into two groups based on whether patients received (group A, 14 patients) or not (group B, 30 patients) dietary prescription for hypophosphatemia. Group A was further divided into two subgroups: group A1 (8 patients), with baseline phosphatemia ≥0.5 mmol/L, treated only with a diet rich in animal phosphorus, and group A2 (6 patients), with baseline phosphatemia ≤0.5 mmol/L, who received a potassium phosphate supplement in addition to the same dietary prescription. Three months after transplantation, group A had a greater increase of phosphatemia compared with group B (group A: 0.58 ± 0.12 vs 0.93 ± 0.22 mmol/L; group B: 0.59 ± 0.11 to 0.8 ± 0.13 mmol/L). Furthermore, in group A2 the increase of phosphatemia was lower than in group A1.

In conclusion, dietary approach supported by dietary counseling was effective in treating post kidney transplantation hypophosphatemia. The results of this pilot study might represent a useful working hypothesis for studies with a larger cohort of enrolled patients in order to confirm for these patients the efficacy of the nutritional approach and of the dietary counseling to post renal transplantation hypophosphatemia.

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Pubblicato

2022-09-14

Come citare

1.
Zattarin A, Francini-Pesenti F, Da Col C, Spinella P, Alessi M, Stefanelli LF, Calò LA. Approccio nutrizionale all’ipofosforemia post-trapianto di rene: uno studio pilota. G Clin Nefrol Dial [Internet]. 14 settembre 2022 [citato 7 febbraio 2023];34(1):74-9. Available at: https://journals.aboutscience.eu/index.php/gcnd/article/view/2472

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Articoli originali
Received 2022-07-26
Accepted 2022-08-08
Published 2022-09-14