New Insights into the Understanding of Gastrointestinal Dysmotility

Bodil Ohlsson; Sabina Janciauskiene

doi:10.33393/dti.2007.1307

Authors

Bodil Ohlsson Department of Clinical Sciences, Gastroenterology Division, Entrance 46, 2nd floor, University Hospital Malmö, Lund University, 20502 Malmö, Sweden.
Sabina Janciauskiene Department of Clinical Sciences, Wallenberg Laboratory, Entrance 46, 2nd floor, University Hospital Malmö, Lund University, 20502 Malmö, Sweden.

DOI:

https://doi.org/10.33393/dti.2007.1307

Keywords:

gonadotropin-releasing hormone (GnRH), oxytocin, chronic intestinal pseudo-obstruction (CIPO), apoptosis

Abstract

Our understanding of the physiology of digestion, absorption, secretion, and motility in the gastrointestinal tract has improved immensely. Today it is well established that the gross functions of the gastrointestinal tract depend on the coordination between the muscles, nerves and hormones. The enteric nervous system (ENS) is involved in most of the physiological and pathophysiological processes in the gastrointestinal tract. Therefore, clinical and experimental studies on the ENS provide the basis for a better understanding of the mechanisms involved in gastrointestinal disorders and promote the development of therapeutic options. This review outlines some of the current views on the role of the ENS and its related hormones in gastrointestinal motility.