Focus on Antimicrobial Resistance (AMR)

AMR has been widely recognized as a global threat to public health with severe socioeconomic impact. Antibiotic-resistance has been responsible for >700,000 deaths every year, and the discovery rate of novel antimicrobials has failed to keep pace with the spread of resistance in clinical settings, generating an urgent need to allocate dedicated resources.

We thank Dr Vijay Kothari from Nirma University (India) who, as Guest Editor, coordinated this focus on AMR: it features articles on antibiotic-resistant infections, particularly those involving pathogens listed by the World Health Organization (WHO) as Priority Pathogens. 

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Editorial
AMR research: a perspective from personal experience
Vijay Kothari

Reviews
Understanding the environmental drivers of clinical azole resistance in Aspergillus species
Pooja Sen, Mukund Vijay, Shweta Singh, Saif Hameed, Pooja Vijayaraghvan

Current molecular approach for diagnosis of MRSA: A meta-narrative review
Yi Xing Sim, Qiao Wei Lee, Aisha Abushelaibi, Kok-Song Lai, Swee Hua Erin Lim, Sathiya Maran

Antibiotic-resistant bacteria originating from the gut may modulate the mucosal immune response during sepsis and septic shock
Swinder Jeet Singh Kalra, Hari Shankar, Nasim Mansoori, Dablu Lal Gupta

Original research articles
MRSA Carriage among Healthcare Workers in a Vietnamese Intensive Care Unit: A Prospective Cohort Study
Thuy Bich Duong, Minh Cuong Duong, James Campbell, Minh Hoang Van Nguyen, Huu Hien Nguyen, Hanh Thi Bich Bui, Chau Van Vinh Nguyen, Anita Heywood