Analisi di impatto sul budget di differenti analoghi ad azione rapida dell’insulina in Italia

Authors

  • Elena P. Lanati MA Provider S.r.l., Milano – Italia
  • Paola La Malfa MA Provider S.r.l., Milano – Italia
  • Arianna Iorio MA Provider S.r.l., Milano – Italia
  • Francesco S. Mennini Università degli Studi di Roma Tor Vergata, Roma – Italia
  • Francesca Fanelli Sanofi Spa, Milano – Italia
  • Sandro Gentile Università degli Studi della Campania “Luigi Vanvitelli”, Napoli – Italia

DOI:

https://doi.org/10.33393/grhta.2018.448

Keywords:

diabetes, insulin glulisine, national expenditure

Abstract

Introduction: Rapid-acting insulins are the current standard of care in diabetes management. Insulin aspart (IA), lispro (IL) and glulisine (IG) demonstrated similar efficacy and safety. However, their impact on the National Health Service (NHS) expenditure could be a relevant differentiating factor. Objective: The study aims to assess the budget impact of IG increased market share in a new scenario vs. current case. Method: A budget impact model built in MS Excel (2010) estimated the impact of IG on the Italian NHS expenditure. Input data were derived from published sources. Pharmaceutical expenditure for considered treatments was estimated on retail or hospital prices and no price modifications were assumed. A scenario analysis was conducted by varying the IG market shares. Results: In the current scenario, IG market share 17.2%, the NHS expenditure is respectively €245-250 million at first and third year. Increasing the IG market share of 35% more of the current scenario, at first year and more of 50% at the following two years, the NHS expenditure reduces to €244.3, €245.0 and €244.8 million in the three years with cumulative, savings around € 8.8 million at third year. The scenario analysis shows that, increasing the IG market shares from 17.2% to 26% at first year, it is possible to achieve savings for almost 10.7 million at third year. Conclusions: IG, besides being as effective and safe as IL and IA, is less expensive and can reduce the financial burden to the Italian NHS up to €8.8 million at third year.

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Published

2018-04-05

How to Cite

1.
Lanati EP, La Malfa P, Iorio A, Mennini FS, Fanelli F, Gentile S. Analisi di impatto sul budget di differenti analoghi ad azione rapida dell’insulina in Italia. Grhta [Internet]. 2018 Apr. 5 [cited 2022 Sep. 26];5(1). Available from: https://journals.aboutscience.eu/index.php/grhta/article/view/448

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Section

Original Research Articles

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