Real World Data use and Applications in the Integrated Management of Rheumatic Disease

Impiego di dati real world nella gestione integrata delle malattie reumatiche

Abstract

Use of real world data is spreading at increasing pace in response to the growing need of ensuring effectiveness and appropriateness in the delivery of health and medical care. Data from clinical trials are essential to define efficacy and safety of medical therapies in experimental conditions, while real world data assume greater relevance when one considers the differences between study populations of clinical trials and people who take the same drug in real life conditions, and the changes that happen over time with the acquisition of new evidence on drugs and treatments. Rheumatoid arthritis is a chronic disease with significant social (direct and indirect) costs that today can be medically managed ensuring both effectiveness and appropriateness. Real world data can contribute significantly to the efficient management of this disease as demonstrated by outstanding examples from Italian registries and databases.