Regional Formularies in Italy: current state and future perspectives


  • Alberto Bortolami Direzione Farmaceutico-Protesica Dispositivi Medici, Area Sanità e Sociale, Regione del Veneto, Venezia - Italy
  • Claudio Jommi Dipartimento di Scienze del Farmaco, Università del Piemonte Orientale, Novara - Italy
  • Filippo Bresciani Market Access, Ipsen
  • Luca Piccoli Direzione Farmaceutico-Protesica Dispositivi Medici, Area Sanità e Sociale, Regione del Veneto, Venezia - Italy
  • Elisa Sangiorgi Area Governo del Farmaco e dei Dispositivi medici, Regione Emilia Romagna - Italy
  • Giovanna Scroccaro Direzione Farmaceutico-Protesica Dispositivi Medici, Area Sanità e Sociale, Regione del Veneto, Venezia - Italy



Italy, Regional Formularies, Regional Therapeutic Committees


Regional Formularies (RF) are considered part of pharmaceutical policies implemented by regions to govern access of medicines to regional market. However, they have been actually challenged, because of their presumed impact on differences of patient’s access across the regions. The paper aimed at investigating the current status of RF and Regional Therapeutic Committees (CTR) and at suggesting/recommending possible reforms.

The current status was investigated through a questionnaire administered to the regional pharmaceutical departments. Recommendations were retrieved from a multi-stakeholder work group carried out on 30-31 March 2023, embedded into a Forum focused on the regional pharmaceutical policies.

Nineteen out of twenty-one regions responded to the survey: 12 use RF, mainly managed by the CTR; the RF frequency of update and the time needed for drugs listing greatly vary across regions; pharmacists, specialists and general practitioners are always represented in CTR, whereas other healthcare professionals and experts are more rarely involved; in 3 regions the CTR does not publish any RF update; the CTR mainly rely, to take decisions, on the dimension of the target population, the cost of therapy compared to alternative treatments and the impact on pharmaceutical expenditure.

The working group recommended to overcome the RFs, if they are merely considered a list of available drugs at regional level, focusing CTR activities to ensure market access and to govern the prescribing behaviour, and strengthening/anticipating the flow of information from the Italian Medicines Agency (AIFA) to the regions, to enable a more efficient approach to local access to drugs.


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How to Cite

Bortolami, A., Jommi, C., Bresciani, F., Piccoli, L., Sangiorgi, E., & Scroccaro, G. (2024). Regional Formularies in Italy: current state and future perspectives. Global and Regional Health Technology Assessment, 11(1), 68–74.



Original Research Articles


Received 2023-10-04
Accepted 2024-01-22
Published 2024-03-08


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