Budget Impact analysis of a new system of care in Parkinson’s disease patients

Authors

  • Chiara Bini Centre for Economics and International Studies-Economic Evaluation and Health Technology Assessment, Faculty of Economics, University of Rome “Tor Vergata”, Rome - Italy https://orcid.org/0000-0001-5704-6542
  • Francesco Saverio Mennini Centre for Economics and International Studies-Economic Evaluation and Health Technology Assessment, Faculty of Economics, University of Rome “Tor Vergata”, Rome - Italy and Institute for Leadership and Management in Health, Kingston University London, Kingston Hill, London - UK https://orcid.org/0000-0002-4738-5505
  • Andrea Marcellusi Centre for Economics and International Studies-Economic Evaluation and Health Technology Assessment, Faculty of Economics, University of Rome “Tor Vergata”, Rome - Italy https://orcid.org/0000-0002-3974-3798
  • Martina Paoletti Centre for Economics and International Studies-Economic Evaluation and Health Technology Assessment, Faculty of Economics, University of Rome “Tor Vergata”, Rome and Department of Health Sciences, University of Genoa, Genoa - Italy https://orcid.org/0000-0002-2564-6698
  • Carlo Tomino Scientific Direction, IRCCS San Raffaele Roma, Rome - Italy https://orcid.org/0000-0003-1823-2195

DOI:

https://doi.org/10.33393/grhta.2022.2413

Keywords:

Apomorphine hydrochloride, Budget Impact Analysis, Economic Evaluation, Parkinson’s Disease

Abstract

Objective: To estimate the economic impact of the introduction of a new care system based on apomorphine and Patient Support Program for motor fluctuations (“on-off” phenomena) in patients with Parkinson’s disease which are not sufficiently controlled by oral anti-Parkinson medication in Italy.

Method: A Budget Impact model was developed to evaluate the new care system in patients with Parkinson’s disease over a 3-years’ time horizon. The comparator treatments included in the analysis were treatments based on apomorphine and levodopa + carbidopa. The analysis was conducted from a National Health Service (NHS) perspective. Costs included in the analysis were acquisition costs and device costs. A deterministic sensitivity analysis was carried out to evaluate the uncertainty of the parameters used. A break-even analysis was conducted to identify the minimum number of subjects that would need to be treated with the new care system to obtain a positive Budget Impact (World With – World Without = 0).

Results: The analysis shows that the introduction of the new care system based on apomorphine could generate a cost saving incurred by the NHS of over € 5.7 million in 3 years. Break-even analysis shows that if it were possible to intercept with the new treatment at least 9 patients treated with apomorphine, there would not be an increase in costs for the NHS.

Conclusion: The new care system would respond to the unmet needs of patients with Parkinson’s disease by generating a reduction in the expenditure incurred by NHS.

References

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Published

2022-09-19

How to Cite

1.
Bini C, Mennini FS, Marcellusi A, Paoletti M, Tomino C. Budget Impact analysis of a new system of care in Parkinson’s disease patients. Grhta [Internet]. 2022 Sep. 19 [cited 2022 Oct. 1];9(1):91-8. Available from: https://journals.aboutscience.eu/index.php/grhta/article/view/2413

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Original Research Articles

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