Long-lasting response with lapatinib treatment: a case report

Risposta persistente in corso di trattamento con lapatinib: un caso clinico

Authors

  • Andrea Milani Divisione di Oncologia Clinica Investigativa (INCO), Candiolo Cancer Institute-FPO-IRCCS, Candiolo, Torino (Italy)
  • Imperia Nuzzolese Divisione di Oncologia Medica-1, Candiolo Cancer Institute-FPO-IRCCS, Candiolo, Torino and Dipartimento di Oncologia, Università di Torino (Italy)
  • Giovanna Chilà Divisione di Oncologia Medica-1, Candiolo Cancer Institute-FPO-IRCCS, Candiolo, Torino and Dipartimento di Oncologia, Università di Torino, Torino (Italy)

DOI:

https://doi.org/10.19156/abtpn.2018.0030

Keywords:

Lapatinib, metastatic breast cancer, brain metastasis, HER2

Abstract

Lapatinib is a small molecule and a reversible inhibitor of HER2, which has shown to be effective on brain lesions in patients with HER2-positive breast cancer relapsed at the central nervous system (CNS). We report the clinical case of a young woman, treated with the combination of lapatinib and capecitabine from September 2009 to today for a metastatic recurrence of HER2-positive breast carcinoma at CNS level and who has achieved a complete response of the encephalic lesion and has not shown disease progression at systemic or CNS level, with excellent tolerance profile (Oncology).

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Published

2018-09-10

How to Cite

Milani, A., Nuzzolese, I., & Chilà, G. (2018). Long-lasting response with lapatinib treatment: a case report: Risposta persistente in corso di trattamento con lapatinib: un caso clinico. AboutOpen, 4(1), 1–4. https://doi.org/10.19156/abtpn.2018.0030

Issue

Vol. 4 No. 1 (2018): January - December 2018

Section

Case report

License

Authors contributing to AboutOpen agree to publish their articles under the Creative Commons NonCommercial 4.0 International License (CC BY-NC 4.0), which allows third parties to copy and redistribute the material providing appropriate credit and a link to the license but does not allow to use the material for commercial purposes and to use the material if it has been remixed, transformed or built upon. 

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