Long-lasting response with lapatinib treatment: a case report
Risposta persistente in corso di trattamento con lapatinib: un caso clinico
DOI:
https://doi.org/10.19156/abtpn.2018.0030Keywords:
Lapatinib, metastatic breast cancer, brain metastasis, HER2Abstract
Lapatinib is a small molecule and a reversible inhibitor of HER2, which has shown to be effective on brain lesions in patients with HER2-positive breast cancer relapsed at the central nervous system (CNS). We report the clinical case of a young woman, treated with the combination of lapatinib and capecitabine from September 2009 to today for a metastatic recurrence of HER2-positive breast carcinoma at CNS level and who has achieved a complete response of the encephalic lesion and has not shown disease progression at systemic or CNS level, with excellent tolerance profile (Oncology).