Hand hygiene for prevention and control of viral infections: the role of Amuchina Gel Xgerm
DOI:
https://doi.org/10.33393/ao.2024.3435Keywords:
Alcohol-based hand sanitizer, Enveloped virus, Infection prevention, Non-enveloped virusAbstract
Introduction: Alcohol-based hand sanitizers are used in healthcare settings, but their efficacy against both enveloped and non-enveloped viruses requires further investigation.
Methods: In this study, viral suspensions composed by the test virus, an interfering substance, and the test product, were exposed to Amuchina Gel Xgerm (100 g of the product contains 74 g of ethanol 96%; Angelini Pharma S.p.A) at 80% dilution in water, according to the European Standard EN14476:2013+A2:2019 – quantitative suspension test for the evaluation of virucidal activity in the medical area – for chemical disinfectants and antiseptics, in the presence of bovine serum albumin 0.3 g/L. The residual viral titers were measured.
Results: Sixty second exposures to the product determined a ≥4 log10 reduction of virus titer in all cases. For adenovirus type 5, human coxsakievirus, herpesvirus 1 and influenza virus A H1N1, a ≥4 log10 reduction of virus titer was obtained already after 30 s. Amuchina Gel Xgerm demonstrated effectiveness against seven virus families, including both enveloped and non-enveloped viruses.
Conclusion: Amuchina Gel Xgerm is a preventive measure against infection spread in healthcare and community settings, contributing to improved healthcare management.
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Copyright (c) 2024 Claudio Cermelli, Elisabetta Blasi, Alessandra Capezzone de Joannon, Maria Ilaria Roselli, Daniele Frollano, Michela Procaccini
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Accepted 2024-12-29
Published 2024-12-31
