Comedone switch and reverse nella patogenesi e nel trattamento dell’acne. Un ruolo per la silimarina?

Comedone switch and reverse in acne pathogenesis and treatment. A role for silimarin?

  • Stefano Veraldi Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano - Italy
  • Mauro Barbareschi Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano - Italy
Keywords: Acne, Comedone switch, Silybum marianum

Abstract

Recent developments in the understanding of pathophysiology of acne are creating new opportunities in the treatment of this disease. In this brief review, we illustrate the role of local inflammation, and LRIG1+ cells in the development of comedone switch, and the potential of silimarin to counteract this process and favour comedone reverse. Preliminary data using Silybum marianum in different studies have shown promising results. Further data from ongoing studies will clarify its role in the long-term treatment of patients with acne.

 

References

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Published
2020-09-04
How to Cite
VeraldiS., & BarbareschiM. (2020). Comedone switch and reverse nella patogenesi e nel trattamento dell’acne. Un ruolo per la silimarina?. AboutOpen, 7(1), 74-75. https://doi.org/10.33393/abtpn.2020.2175