Case 1 – Multiple brain metastases from ovarian cancer: a case report

 

Authors

  • C. Marchetti Department of Gynecological and Obstetrical Sciences and Urological Sciences, Università “Sapienza” of Rome, Rome, Italy.
  • R. Iadarola Department of Gynecological and Obstetrical Sciences and Urological Sciences, Università “Sapienza” of Rome, Rome, Italy.
  • L. Vertechy Department of Gynecological and Obstetrical Sciences and Urological Sciences, Università “Sapienza” of Rome, Rome, Italy.
  • L. Di Francesco Department of Gynecological and Obstetrical Sciences and Urological Sciences, Università “Sapienza” of Rome, Rome, Italy.
  • V. Borzillo Division of Radiotherapy, Department of Diagnostic Imaging and Radiation Therapy and Metabolic, Istituto Nazionale Tumori IRCCS “Fondazione G. Pascale”, Naples, Italy.
  • C. Pisano Division of Oncology, Department of Urology and Gynecology, Istituto Nazionale Tumori IRCCS “Fondazione G. Pascale”, Naples, Italy.

Abstract

58-year-old woman with a history of epithelial ovarian cancer, who manifested seizure disorder, characterized by sudden stiffening of her entire body with loss of consciousness. The imaging revealed the presence of multiple secondary lesions scattered throughout the brain parenchyma bilaterally in the supra and infratentorial areas; other evidences of disease were localized in the lung and abdominal cavity with signs of peritoneal carcinomatosis. She received a whole brain radiation therapy followed by adjuvant chemotherapy with carboplatin and paclitaxel. To date, after 11 months from initial diagnosis of brain metastasis, the patient is still well, without neurological symptoms, or local progression, in the brain or the abdomen.