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Founded in October 2013, Cancer Breaking News (CBN) had a primary goal to promote the debate and interaction between young physicians, leaders and qualified experts in the field of oncology. Its activity has been discontinued at the end of 2017 and we now offer the journal contents under open access terms. Cancer Breaking News has been a valuable point of reference for both expert and young specialists alike for the high scientific value of its contents and has published relevant reviews in the field of oncology, original clinical research studies, interviews with experts, and clinical cases commented by key Italian and international opinion leaders. It also included articles on the methodological analysis of clinical studies to identify their strengths and weaknesses, as well as a section on translational research. The journal was published thanks to the unconditional contribution of AstraZeneca, PharmaMar, and Roche.