Polignano, M., Lasala, R., Giannini, R., Ucciero, A., Romagnoli, A., Isgrò, V., Santoleri, F. and Costantini, A. (2025) “From data to evidence: the evolving role of observational studies and target trial emulation in regulatory decision-making”, AboutOpen, 12(1), pp. 43–46. doi: 10.33393/ao.2025.3645.