Biological effects of resin monomers on oral cell populations: descriptive analysis of literature

Authors

  • S Pagano Department of Biomedical and Surgical Sciences, Odontostomatological University Centre: Chair Prof. Stefano Cianetti, University of Perugia, Perugia
  • M Coniglio Department of Biomedical and Surgical Sciences, Odontostomatological University Centre: Chair Prof. Stefano Cianetti, University of Perugia, Perugia
  • C Valenti Department of Biomedical and Surgical Sciences, Odontostomatological University Centre: Chair Prof. Stefano Cianetti, University of Perugia, Perugia
  • P Negri Department of Biomedical and Surgical Sciences, Odontostomatological University Centre: Chair Prof. Stefano Cianetti, University of Perugia, Perugia
  • G Lombardo Department of Biomedical and Surgical Sciences, Odontostomatological University Centre: Chair Prof. Stefano Cianetti, University of Perugia, Perugia
  • E Costanzi Department of Experimental Medicine, Section of Biosciences and Medical Embryology, University of Perugia, Perugia
  • S Cianetti Department of Biomedical and Surgical Sciences, Odontostomatological University Centre: Chair Prof. Stefano Cianetti, University of Perugia, Perugia
  • A Montaseri Anatomical Sciences Department, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz
  • L Marinucci Department of Experimental Medicine, Section of Biosciences and Medical Embryology, University of Perugia, Perugia

DOI:

https://doi.org/10.23804/ejpd.2019.20.03.11

Keywords:

Cytotoxicity, Immunological effect, Resin monomers

Abstract

AIM: Recently, the application of restorative materials containing metacrilate monomers in the conservative and paediatric dentistry has focused on the possible negative effects due to the use of these composites. In particular the release of monomers from reconstructions as a result of an insufficient polymerisation, can spread along the mucosal and dental tissues with potential immunological ed cytotoxic effects. Regarding to the importance of this issue, the aim of this study is to provide a descriptive review of the literature on potential local and systemic interactions of metacrylic and acrylic monomers with the immune system, both in vitro and in vivo.